METHOD OF PHOTODYNAMIC THERAPY WITH INTRADERMAL PHOTOSENSITIZATION
	NIMAEV V V; NIKONOV S D; BREDIKHIN D A; MAYOROV A P; CHERNOPYATOV D I
	2020-07-15
专利权人	UNIV NOVOS NAT RES STATE (UYNS-Non-standard) ; AS SIBE CYTOLOGY & GENETICS INST (ASIC-Non-standard) ; AS SIBE LASER PHYS INST (ASIL-Non-standard)
申请日期	2020-07-15
专利号	RU2750975-C1
成果简介	NOVELTY - Invention relates to medicine, namely to dermatology, gynecology, oncology, and can be used for photodynamic therapy with intradermal photosensitization of skin lesions and photoaging skin. For this, non-ablative photothermolysis of the affected area is carried out by scanning laser radiation in the range of 970-2000 nm with an average power of no more than 4 W in a pulsed mode with a frequency of 50 Hz, a pulse duration of 10 ms and a pulse energy of 0.0 6-0.1 J. Then, for no more than 3 hours, a photosensitizer, which is a derivative of chlorin E6, is applied to the skin, after which the excess of the photosensitizer is removed and the photosensitized area is irradiated with scanning laser radiation with a wavelength of 662 nm with an average power of 1-2 W in a pulse-periodic mode with a frequency of 5 Hz and pulse duration 100 ms. The course of treatment includes one or more procedures, depending on the degree of skin damage by the pathological process. USE - Medicine. ADVANTAGE - Method allows to increase the efficiency of photodynamic therapy of age-related skin changes, benign, malignant, infectious-inflammatory, degenerative-dystrophic diseases of the skin due to the increased depth of intradermal transport of the photosensitizer through microthermal zones with a sparing nature of the photodynamic reactions induced in tissues and a reduction in the duration of the photosensitization process and the number of FF sessions. 5 cl, 1 tbl, 1 ex
IPC 分类号	A61K-031/409 ; A61N-005/067 ; A61P-017/12
国家	俄罗斯
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/23135
专题	中国科学院新疆生态与地理研究所
作者单位	1.UNIV NOVOS NAT RES STATE (UYNS-Non-standard) 2.AS SIBE CYTOLOGY & GENETICS INST (ASIC-Non-standard) 3.AS SIBE LASER PHYS INST (ASIL-Non-standard)
推荐引用方式 GB/T 7714	NIMAEV V V,NIKONOV S D,BREDIKHIN D A,et al. METHOD OF PHOTODYNAMIC THERAPY WITH INTRADERMAL PHOTOSENSITIZATION. RU2750975-C1[P]. 2020.

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