Evaluating transdermal permeability of chemicals from solutions, based on the calculation of the permeability coefficient of a chemical using a linear regression equation
2021-05-17
专利权人SIGNAL FEDERAL STATE UNITARY ENTERPRISE (SIGN-Non-standard)
申请日期2021-05-17
专利号RU2021113893-A
成果简介NOVELTY - Evaluating transdermal permeability of chemicals from solutions, based on the calculation of the permeability coefficient of a chemical using a linear regression equation, characterized in that the predictors of the regression equation use the molecular weight and the number of hydrogen bond acceptors of the substance and the solvent, which are obtained from their empirical formulas, for multicomponent solutions predictors are calculated as the sum of the properties of all components, weighted by their mole fractions, increasing the accuracy of calculating the permeability coefficient is achieved by comprising indicator predictors in the regression equation, determined by the form of application of the substance and the type of animal to which it is applied, with the corresponding coefficients for each indicator. USE - The method is useful for evaluating transdermal permeability of chemicals from solutions. ADVANTAGE - None given.
IPC 分类号A61K-009/00
国家俄罗斯
专业领域医药卫生
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/22854
专题中国科学院新疆生态与地理研究所
作者单位
SIGNAL FEDERAL STATE UNITARY ENTERPRISE (SIGN-Non-standard)
推荐引用方式
GB/T 7714
IVANOV D G,KOMAROVA V V,KRUGLOVA A A,et al. Evaluating transdermal permeability of chemicals from solutions, based on the calculation of the permeability coefficient of a chemical using a linear regression equation. RU2021113893-A[P]. 2021.
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