| METHOD FOR RESTORING THE FUNCTIONS OF THE SPINAL CORD AFTER TRANSECTION THEREOF, USING PEG-CHITOSAN CONJUGATE | |
| 2021-07-08 | |
| 专利权人 | UNIV STAVROPOL MED (UYST-Non-standard) ; LEBENSHTEIN G M V (LEBE-Individual) |
| 申请日期 | 2021-07-08 |
| 专利号 | RU2782119-C1 |
| 成果简介 | NOVELTY - Invention relates to the field of medicine, namely, experimental medicine, neurosurgery, and regenerative medicine, and can be used to restore the functions of the spinal cord after transection thereof. PEG-chitosan is synthesised by covalent binding of PEG with cross-linked chitosan. After making an access to the spinal cord and slightly incising the pia mater, a PEG-chitosan conjugate agent synthesised by covalent binding is injected into the subdural space; the spinal cord is transected and resected within the viable part. The PEG-chitosan conjugate is then injected into the subdural space and spinal cord diastasis in the amount necessary to cover the surface of segments of the spinal cord and to fill the diastasis. The segments of the spinal cord are approximated, sutures are applied to the pia mated, the dura mater is sutured, and an aqueous solution of polyethylene glycol is injected intravenously. USE - Medicine. ADVANTAGE - Method ensures the restoration of the functional and morphological integrity of the spinal cord after complete or partial transection thereof or in the event of contusion or rupture thereof, due to the intraoperative introduction of a chitosan and polyethylene glycol conjugate into the spinal cord diastasis. 1 cl |
| IPC 分类号 | A61B-017/00 ; A61K-031/722 ; A61K-031/745 ; A61P-025/00 ; G09B-023/28 |
| 国家 | 俄罗斯 |
| 专业领域 | 医药卫生 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/22832 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | 1.UNIV STAVROPOL MED (UYST-Non-standard) 2.LEBENSHTEIN G M V (LEBE-Individual) |
| 推荐引用方式 GB/T 7714 | LEBENSHTEIN G M V,BOTASHEVA V S,KOVALYOV D A,et al. METHOD FOR RESTORING THE FUNCTIONS OF THE SPINAL CORD AFTER TRANSECTION THEREOF, USING PEG-CHITOSAN CONJUGATE. RU2782119-C1[P]. 2021. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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