Visualization of parathyroid glands involves ultrasonically-treating carbon black particles in polyvinylpyrrolidone solution, introducing obtained suspension into area of parathyroid glands, and performing intraoperative identification of glands due to selective staining of tissues with suspension
	PETROV V A; KAMKHA M M; SUKHANOV I V; SEMIKOV V I
	2022-03-18
专利权人	GI-GRAN LLC (GIGR-Non-standard)
申请日期	2022-03-18
专利号	RU2022107081-A
成果简介	NOVELTY - Visualization of parathyroid glands involves (i) preparing a suspension of carbon particles by preparing a solution containing 0.3-0.5 wt.% polyvinylpyrrolidone having a molecular weight of 10-60 kDa in sodium phosphate buffer as a solvent, and having a concentration of 0.9 wt.%, adding powder of carbon black particles having an average particle size of 20-80 nm and a heavy metal content of less than 5 ppm to the solution at a final concentration of 20-70 mg/ml, ultrasonically-treating twice for 20 minutes in an ultrasonic bath with a power of 240-600 W, stirring the mixture on a magnetic stirrer at room temperature for 6 hours to obtain particles having an average particle size of 120-250 nm, and filtering using a syringe filter with a pore size of 0.45 μ m to remove large aggregates, (ii) introducing the suspension into area of parathyroid glands, and (iii) performing intraoperative identification of parathyroid glands due to selective staining of tissues with the suspension. USE - Visualization of parathyroid glands. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for preparation of the suspension of carbon particles.
IPC 分类号	A61B-017/00
国家	俄罗斯
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/22644
专题	中国科学院新疆生态与地理研究所
作者单位	GI-GRAN LLC (GIGR-Non-standard)
推荐引用方式 GB/T 7714	PETROV V A,KAMKHA M M,SUKHANOV I V,et al. Visualization of parathyroid glands involves ultrasonically-treating carbon black particles in polyvinylpyrrolidone solution, introducing obtained suspension into area of parathyroid glands, and performing intraoperative identification of glands due to selective staining of tissues with suspension. RU2022107081-A[P]. 2022.

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