| ADENOSINE DERIVATIVES-INHIBITORS OF REPRODUCTION OF VIRUSES RELATED TO GENUS FLAVIVIRUS | |
| 2023-04-28 | |
| 专利权人 | ROBOTICS & TECH CYBERNETICS CENT RES (ROBO-Non-standard) ; ENGELHARDT INST MOLECULAR BIOLOGY (ENGE-Non-standard) |
| 申请日期 | 2023-04-28 |
| 专利号 | RU2828777-C1 |
| 成果简介 | NOVELTY - Invention relates to a modified nucleoside analogue of formula (I) or a pharmaceutically acceptable salt thereof, where R is selected independently and represents -C≡C-C3-6-cycloalkyl, -C≡C-C3-6-cycloalkenyl, -C≡C-C6-aryl substituted with -C≡C-C6-aryl with at least one substitute selected from partially or completely halogenated -C1-5-alkyl, phenyl substituted with at least one substitute selected from -C1-5-alkyl, partially or completely halogenated -C1-5-alkyl. Invention also relates to use of a compound of formula (I) as a virus reproduction inhibitor related to genus Flavivirus, use of a compound of formula (I) for preparing a pharmaceutical composition for treating and/or preventing diseases caused by a virus of the genus Flavivirus, and a pharmaceutical composition based on the compound of formula (I) for the treatment and/or prevention of diseases caused by a virus of the genus Flavivirus. USE - Organic chemistry; pharmacology; medicine. ADVANTAGE - Obtaining a compound of formula (I), characterized by high efficiency in inhibiting reproduction of viruses of the genus Flavivirus. 12 cl, 4 tbl, 11 ex |
| IPC 分类号 | A61K-031/52 ; A61P-031/14 ; C07D-473/34 ; C07H-019/167 |
| 国家 | 俄罗斯 |
| 专业领域 | 化学化工 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/21957 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | 1.ROBOTICS & TECH CYBERNETICS CENT RES (ROBO-Non-standard) 2.ENGELHARDT INST MOLECULAR BIOLOGY (ENGE-Non-standard) |
| 推荐引用方式 GB/T 7714 | GORYASHCHENKO A S,DRENICHEV M S,ZENCHENKO A A,et al. ADENOSINE DERIVATIVES-INHIBITORS OF REPRODUCTION OF VIRUSES RELATED TO GENUS FLAVIVIRUS. RU2828777-C1[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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