OPHTHALMIC MEDICINAL FILM BASED ON BIODEGRADABLE POLYMER AND METHOD FOR ITS PREPARATION
	TURAEVA A R; BAKHRUSHINA E O; DEMINA N B; KRASNYUK I I
	2023-07-05
专利权人	UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
申请日期	2023-07-05
专利号	RU2831474-C1
成果简介	NOVELTY - Group of inventions relates to a composition for preparing an ophthalmic medicinal film based on a biodegradable polymer, characterized by the fact that it contains components taken at the following ratio, wt.%: dexpanthenol—2–3.0, hyaluronic acid—2.0, hydroxyethyl cellulose—0.5–1.5, poloxamer—0.5, glycerine—2.0, purified water—the rest, and also relates to a method of producing an eye film using a composition, characterized by the fact that in a volume of water purified in a reactor without heating, dexpanthenol 2.0–3.0 wt.% and glycerol 2.0 wt.% are dissolved while stirring at 40–60 rpm for 10–15 minutes, hyaluronic acid 2.0 wt.%, hydroxyethyl cellulose 0.5–1.5 wt.%, poloxamer 0.5 wt.%, stirring is continued at temperature of 20 °C for 30–40 minutes until complete dissolution and homogeneous distribution of components, obtained solution of active and auxiliary substances is poured into sterile molds and dried in a thermostat at temperature of 35–37 °C for 8–9 hours to a residual moisture content of 7%, finished film layer is cut into oval films with size of 5×6 mm and packed into a contour-cellular mono-package. USE - Medicine; pharmaceutics. ADVANTAGE - Group of inventions provides developing a composition for preparing an ophthalmic drug based on a biodegradable polymer. 2 cl, 2 tbl, 19 ex
IPC 分类号	A61K-031/16 ; A61K-031/728 ; A61K-047/10 ; A61K-047/34 ; A61K-047/38 ; A61P-027/02
国家	俄罗斯
专业领域	生物科学
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/21388
专题	中国科学院新疆生态与地理研究所
作者单位	UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
推荐引用方式 GB/T 7714	TURAEVA A R,BAKHRUSHINA E O,DEMINA N B,et al. OPHTHALMIC MEDICINAL FILM BASED ON BIODEGRADABLE POLYMER AND METHOD FOR ITS PREPARATION. RU2831474-C1[P]. 2023.

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