preparing gold nanoparticles for anticancer activity against head and neck squamous cell carcinoma, comprises preparing crude flower extract of Madhuca indica in ethanol, mixing the flower extract of Madhuca indica with the aqueous solution of tetrachloroauric(III) acid trihydrate, centrifuging
	SAHA D; DAS G; MURMU N
	2023-07-19
专利权人	CHITTARANJAN NAT CANCER INST (CHIT-Non-standard)
申请日期	2023-07-19
专利号	IN202331048534-A
成果简介	NOVELTY - Preparing gold nanoparticles comprise: (a) preparing a crude flower extract of Madhuca indicain ethanol; (b) providing an aqueous solution of tetrachloroauric(III) acid trihydrate (HAuCl4.3H2O); (c) mixing the flower extract of Madhuca indicawith the aqueous solution of tetrachloroauric(III) acid trihydrate with constant stirring to obtain the colloidal solution containing gold nanoparticles; and (d) centrifuging the colloidal solution to obtain gold nanoparticles. USE - Method for preparing gold nanoparticles for anticancer activity against head and neck squamous cell carcinoma and oral squamous cell carcinoma (claimed). No biological data given. ADVANTAGE - The method provides gold nanoparticles that eliminate the use of toxic chemicals, can be used in combination with existing drugs, to enhance its efficiency as well to reduce the side effects over long term usage of chemical drugs, can serve as effective carriers for delivering anti-cancer agents to tumor sites, exhibits small size, large surface area and unique physicochemical properties for efficient loading and delivery of therapeutic agents, thus improving their efficacy. The gold nanoparticles exhibit excellent biocompatibility, which are less likely to induce adverse reaction or toxicity in body, and exhibits synergistic effect. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a gold nanoparticles showing anticancer activity against head and neck squamous cell carcinoma and oral squamous cell carcinoma, having a particle size of 15-30 nm and are monodispersed spherical particles having average size of 16-25 nm.
IPC 分类号	B01J-023/52 ; B01J-035/02 ; B01J-037/16 ; B82Y-005/00 ; G01N-033/553
国家	印度
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/21241
专题	中国科学院新疆生态与地理研究所
作者单位	CHITTARANJAN NAT CANCER INST (CHIT-Non-standard)
推荐引用方式 GB/T 7714	SAHA D,DAS G,MURMU N. preparing gold nanoparticles for anticancer activity against head and neck squamous cell carcinoma, comprises preparing crude flower extract of Madhuca indica in ethanol, mixing the flower extract of Madhuca indica with the aqueous solution of tetrachloroauric(III) acid trihydrate, centrifuging. IN202331048534-A[P]. 2023.

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