| Purifying nortriptyline or its salts such as nortriptyline hydrochloride; that is used for providing antidepressant effects by inhibiting reuptake of norepinephrine and serotonin in CNS nerve terminals; used for ameliorating depressive symptoms; treating nocturnal enuresis of children | |
| 2023-07-24 | |
| 专利权人 | VASUDHA PHARMA CHEM LTD (VASU-Non-standard) |
| 申请日期 | 2023-07-24 |
| 专利号 | IN202341049589-A |
| 成果简介 | NOVELTY - Purifying nortriptyline or its salts comprises: heating Nortriptyline or its salts with a reducing agent. USE - Process for purifying nortriptyline or its salts such as nortriptyline hydrochloride (claimed); that is used for providing antidepressant effects by inhibiting reuptake of norepinephrine and serotonin in central nervous system (CNS) nerve terminals; used for ameliorating depressive symptoms; treating nocturnal enuresis of children. No biological data given. ADVANTAGE - The process reduces N-nitroso impurity; employs nortriptyline that is free from carcinogenic/genotoxic nitrosamine drug substance-related impurities (NDSRIs) and their carcinogenic precursor impurities. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a process for the purification of nortriptyline hydrochloride, comprising: heating Nortriptyline hydrochloride with sodium borohydride. |
| IPC 分类号 | A61K-039/385 ; C07C-209/00 ; C07C-209/36 ; C07C-045/00 ; C07C-049/675 ; C07C-067/00 ; C07C-069/738 ; C07C-069/76 |
| 国家 | 印度 |
| 专业领域 | 医药卫生 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/21156 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | VASUDHA PHARMA CHEM LTD (VASU-Non-standard) |
| 推荐引用方式 GB/T 7714 | MADAKA J R,KUNAPARAJU P V,BALUSU P K,et al. Purifying nortriptyline or its salts such as nortriptyline hydrochloride; that is used for providing antidepressant effects by inhibiting reuptake of norepinephrine and serotonin in CNS nerve terminals; used for ameliorating depressive symptoms; treating nocturnal enuresis of children. IN202341049589-A[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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