System for solvent selection method in liquid chromatography has input/output device for accepting user input of test sample data in compound identifier format, and processing unit comprising network management unit, processor, search unit and mathematical module
	KULKARNI M M; SHAH J S; MAHESHWARI D G; SHAH S; SHAH D B; SINGH Y R
	2023-08-01
专利权人	LJ INST PHARMACY (LJPH-Non-standard)
申请日期	2023-08-01
专利号	IN202321051617-A
成果简介	NOVELTY - System comprises: input/output (I/O) device (1) for accepting user input of test sample data in compound identifier (CID) format; and processing unit (2) comprising network management unit (4), a processor (3) with a search function library and an instruction manual library, search unit (7), and mathematical module. The memory unit comprises data management system, random forest model (RFM) memory, solvent library, learning memory and training memory. The processor is for retrieving the simplified molecular-input line-entry system format of the test sample based on the inputted CID from online databases using the search function library and evaluating various prediction parameters for a solvent using algorithms from the instruction manual library. The search unit is for utilizing the RFM, and identifying the two most solvents for the test sample from the solvent library based on the prediction parameters evaluated by the processor. USE - The system is useful for solvent selection method in liquid chromatography (claimed) for drug discovery and development, drug analysis and purification of drug compounds, forensic labs for analysis of various samples, quality control laboratories for analyzing food samples, universities and research institutions, biochemistry, medicinal chemistry and analytical chemistry. ADVANTAGE - The system: streamlines and automates the process of solvent selection for HPLC and Reversed-phase HPLC, thus increasing efficiency and reducing human errors; incorporates machine learning techniques, specifically the random forest model and artificial neural networks, to predict the most solvent based on various parameters of a given test sample, thus enhancing the accuracy of the solvent selection process; creates a robust memory system with various types of memories serving specific functions, i.e. solvent library with a predefined database structure of all solvents used in liquid chromatography, thus enabling the system to learn and train for improved results over time; develops a network management unit that provides internet access to the processor, thus enabling the system to fetch the simplified molecular-input line-entry system format of a given CID from online databases, thus enhancing the versatility and user-friendliness of the system; and utilizes data from the training memory to refine the model and optimize the solvent selection results, thus significantly reducing the time spent on trial and error and increasing the overall effectiveness of the chromatography tests. DESCRIPTION OF DRAWING(S) - The figure shows a schematic view of system. 1Input or output device 2Processing unit 3Processor 4Network management unit 7Search unit
IPC 分类号	G01N-030/06 ; G01N-030/34 ; G01N-030/36 ; G01N-030/74 ; G01N-030/86 ; G16C-020/50 ; G16C-020/70
国家	印度
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/21024
专题	中国科学院新疆生态与地理研究所
作者单位	LJ INST PHARMACY (LJPH-Non-standard)
推荐引用方式 GB/T 7714	KULKARNI M M,SHAH J S,MAHESHWARI D G,et al. System for solvent selection method in liquid chromatography has input/output device for accepting user input of test sample data in compound identifier format, and processing unit comprising network management unit, processor, search unit and mathematical module. IN202321051617-A[P]. 2023.

条目包含的文件
条目无相关文件。

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。