| Producing selexipag by obtaining 4-(N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino)-1-butanol by reacting 5-chloro-2,3-diphenylpyrazine with 4-isopropylamino-1-butanol in presence of alkali metal iodide e.g. potassium iodide and sodium iodide | |
| 2023-08-04 | |
| 专利权人 | RIHOPE RES INST HYGIENE OCCUPATIONAL PAT (RIHO-Non-standard) |
| 申请日期 | 2023-08-04 |
| 专利号 | RU2023120540-A |
| 成果简介 | NOVELTY - Method for producing selexipag involves obtaining 4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]-1-butanol by reacting 5-chloro-2,3-diphenylpyrazine with 4-isopropylamino-1-butanol in the presence of an alkali metal iodide chosen from potassium iodide, sodium iodide, and lithium iodide. USE - The method is useful for producing selexipag. ADVANTAGE - The method enables production of selexipag in an environmentally-friendly manner. |
| IPC 分类号 | A61K-031/4965 ; C07D-241/20 |
| 国家 | 俄罗斯 |
| 专业领域 | 化学化工 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/20973 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | RIHOPE RES INST HYGIENE OCCUPATIONAL PAT (RIHO-Non-standard) |
| 推荐引用方式 GB/T 7714 | ABZIANIDZE V V,BOGACHENKOV A S,KRIVOROTOV D V,et al. Producing selexipag by obtaining 4-(N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino)-1-butanol by reacting 5-chloro-2,3-diphenylpyrazine with 4-isopropylamino-1-butanol in presence of alkali metal iodide e.g. potassium iodide and sodium iodide. RU2023120540-A[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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