Zinc oxide nanoparticle for inhibiting growth of bacteria such as Escherichia coli, and fungi such as Candida albicans, comprises weed extract obtained from Rhamnus triquetra, chitosan, and metallic nanoparticle solution, where metallic nanoparticles include silver, gold, copper, and zinc
	MANN N A; SHARMA R; THAKUR N; ALTABBAA S
	2023-08-07
专利权人	UNIV SHOOLINI BIOTECHNOLOGY & MANAGEMENT (USLN-C)
申请日期	2023-08-07
专利号	IN202311052779-A
成果简介	NOVELTY - Zinc oxide nanoparticle comprises weed extract, chitosan, and metallic nanoparticle solution, where zinc oxide nanoparticles have a size of 20-35 nm. The chitosan is a natural polymer, the metallic nanoparticles include silver, gold, copper and zinc. The weed extract is obtained from Rhamnus triquetra. USE - Zinc oxide nanoparticle for inhibiting growth of bacteria such as Escherichia coliand Staphylococcus aureus, and fungi such as Candida albicans, and Rosellinia necatrix. ADVANTAGE - The zinc oxide nanoparticle ensures improved stability, biocompatibility, and can be prepared with high purity without the need for toxic chemicals and solvents, in simple, safe, scalable, environmentally friendly, and cost-effective manner. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method of preparing a chitosan-coated metallic nanoparticles, which comprises: (a) preparing chitosan solution by dissolving 700 mg chitosan in 1% glacial acetic acid; (b) preparing metal precursor solution by dissolving 0.05 M zinc nitrate in 100 mL distilled water and stirring the mixture at 80℃ for 30 minutes; (c) adding 10 mL chitosan solution dropwise to a precursor solution of step (b); (d) heating 15 mL leaf extract taken from leaves of Lantana camaraand Rhamnus triquetrain water bath at 45℃ for 30 minutes; (e)adding leaves extract of step (d) to the solution of step (a) and magnetically stirring for 1 hour; (f) adding 1M solution of sodium hydroxide to the solution of step (e) followed by stirring for an additional period of 2 hours, resulting in a color change of the mixture; (g) leaving the suspension from step (f) undisturbed overnight in a dark environment to facilitate the formation of precipitates; (h) centrifuging the suspension of step (g) at 4000 revolutions/minute for 40 minutes to form pellet; (i) washing the pellet of step (h) with distilled water to remove impurities and subsequently drying in oven at 60℃ for 12 hours; and (j) transferring the dried pellet into a clean bottle for further storage.
IPC 分类号	A61K-036/48 ; A61K-047/36 ; A61K-009/51 ; A61P-031/04 ; B82Y-030/00 ; C08B-037/08
国家	印度
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/20944
专题	中国科学院新疆生态与地理研究所
作者单位	UNIV SHOOLINI BIOTECHNOLOGY & MANAGEMENT (USLN-C)
推荐引用方式 GB/T 7714	MANN N A,SHARMA R,THAKUR N,et al. Zinc oxide nanoparticle for inhibiting growth of bacteria such as Escherichia coli, and fungi such as Candida albicans, comprises weed extract obtained from Rhamnus triquetra, chitosan, and metallic nanoparticle solution, where metallic nanoparticles include silver, gold, copper, and zinc. IN202311052779-A[P]. 2023.

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