METHOD FOR EXPERIMENTAL MODELING OF PERI-IMPLANT INFECTION OF LONG BONES
2023-08-08
专利权人SERGEEV G K (SERG-Individual)
申请日期2023-08-08
专利号RU2824017-C1
成果简介NOVELTY - Invention relates to a method for experimental simulation of peri-implant infection of long bones. A vertical incision of the skin and subcutaneous fat is performed within a greater trochanter of the femur in laboratory rats under general anesthesia. Then in the area of greater trochanter, trepanation of femur with access into medullary canal is performed. Into the medullary canal cavity through the trephine opening in the greater trochanter region, implant of 2.5 cm is introduced, on the surface of which microbial biofilms are pre-formed by immersion in an agar medium with a culture of S. aureus 108 in 1 ml. Then the operative wound is closed tightly and in layers. USE - Veterinary science; experimental medicine. ADVANTAGE - Invention provides improved method for simulating peri-implant infection and subsequent osteomyelitis of long bones, increased reliability of the obtained data, increased labor productivity, reduced consumption of anesthetic preparations and minimization of their adverse side effects on the laboratory animal organism. 1 cl, 1 ex
IPC 分类号A61B-017/56 ; G09B-023/28
国家俄罗斯
专业领域农业科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/20914
专题中国科学院新疆生态与地理研究所
作者单位
SERGEEV G K (SERG-Individual)
推荐引用方式
GB/T 7714
SERGEEV G K,SERGEEV K S,MALCHEVSKY V A. METHOD FOR EXPERIMENTAL MODELING OF PERI-IMPLANT INFECTION OF LONG BONES. RU2824017-C1[P]. 2023.
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