Amorphous solid dispersion used for preventing and treating diseases, e.g., gastroesophageal reflux disease (GERD), peptic ulcer, gastric and duodenal ulcer, Helicobacter pylori infection, dyspepsia, Zollinger-Ellison syndrome, nausea, esophagitis, and asthma, comprises tegoprazan, and excipient
	VYAS H D; MANDE H M; MEHTA T B; THAKRAR V H
	2023-08-19
专利权人	AMI LIFESCI PRIVATE LTD (AMIL-Non-standard)
申请日期	2023-08-19
专利号	IN202321055693-A
成果简介	NOVELTY - Amorphous solid dispersion comprises: tegoprazan, and excipient. USE - Amorphous solid dispersion used for preventing and treating diseases, e.g., gastroesophageal reflux disease (GERD), peptic ulcer, gastric ulcer and a duodenal ulcer, Helicobacter pylori infection, dyspepsia, Zollinger-Ellison syndrome, nausea, esophagitis, and asthma. No biological data given. ADVANTAGE - The amorphous solid dispersion is stable under a long-term and stress storage condition; excellent photostability; low hygroscopicity; and improve solubility. DETAILED DESCRIPTION - INDEPENDENT CLAIMS are included for: 1. a process for the preparation of amorphous solid dispersion, which involves: (a) providing a mixture of tegoprazan and excipient in solvent; (b) removing the solvent from the mixture; and (c) isolating amorphous solid dispersion of tegoprazan; and 2. a pharmaceutical composition, which comprises: amorphous solid dispersion of tegoprazan, and excipients.
IPC 分类号	A61K-031/4184 ; A61K-009/14 ; A61K-009/16
国家	印度
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/20755
专题	中国科学院新疆生态与地理研究所
作者单位	AMI LIFESCI PRIVATE LTD (AMIL-Non-standard)
推荐引用方式 GB/T 7714	VYAS H D,MANDE H M,MEHTA T B,et al. Amorphous solid dispersion used for preventing and treating diseases, e.g., gastroesophageal reflux disease (GERD), peptic ulcer, gastric and duodenal ulcer, Helicobacter pylori infection, dyspepsia, Zollinger-Ellison syndrome, nausea, esophagitis, and asthma, comprises tegoprazan, and excipient. IN202321055693-A[P]. 2023.

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