Preparing 4-amino-5-methyl-1H-pyridine-2-one for use as intermediate of finerenone, comprises reacting 2-chloro-5-methyl-4-aminopyridine with base in presence of water
	YEOLA G B; PATEL G B
	2023-08-22
专利权人	AVENTUS LABS LLP (AVEN-Non-standard)
申请日期	2023-08-22
专利号	IN202321056185-A
成果简介	NOVELTY - Preparing 4-amino-5-methyl-1H-pyridine-2-one (I) comprises reacting 2-chloro-5-methyl-4-aminopyridine (II) with base in presence of water. USE - Method for preparing 4-amino-5-methyl-1H-pyridine-2-one for use as intermediate of finerenone. ADVANTAGE - The method provides 4-amino-5-methyl-1H-pyridine-2-one with high yield and high purity, under mild reaction conditions, in simple, environmentally friendly, and cost-effective manner. DETAILED DESCRIPTION - Preparing 4-amino-5-methyl-1H-pyridine-2-one of formula (I) comprises reacting 2-chloro-5-methyl-4-aminopyridine of formula (II) with base in presence of water. An INDEPENDENT CLAIM is included for a method for purifying 4-amino-5-methyl-1H-pyridine-2-one (I) in polar aprotic solvents.
IPC 分类号	A61K-031/4412 ; A61K-031/4439 ; A61P-025/18 ; C07D-213/64 ; C07D-213/73 ; C07D-471/04
国家	印度
专业领域	医药卫生
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/20728
专题	中国科学院新疆生态与地理研究所
作者单位	AVENTUS LABS LLP (AVEN-Non-standard)
推荐引用方式 GB/T 7714	YEOLA G B,PATEL G B. Preparing 4-amino-5-methyl-1H-pyridine-2-one for use as intermediate of finerenone, comprises reacting 2-chloro-5-methyl-4-aminopyridine with base in presence of water. IN202321056185-A[P]. 2023.

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