| METHOD OF PRODUCING ALLOGENIC AND XENOGENIC MINERAL BONE COMPONENT FROM HUMAN AND ANIMAL DENTAL TISSUES | |
| 2023-09-04 | |
| 专利权人 | UNIV SAMARA NAT RES (UYSA-Non-standard) |
| 申请日期 | 2023-09-04 |
| 专利号 | RU2829913-C1 |
| 成果简介 | NOVELTY - Invention relates to the development of medicinal preparations for the correction of bone metabolism disorders and the manufacture of biomaterials for the restoration of maxillofacial defects, and relates to a method of producing a mineral bone component from human and animal teeth. Proposed method comprises treating teeth with a hydrogen peroxide solution, demineralizing the obtained material in a hydrochloric acid solution, filtering the obtained solution through a cellulose filter, neutralizing, separation of the precipitate formed after neutralization by centrifugation and washing with distilled water, wherein the teeth are mechanically cleaned from soft tissues, food residues and plaque, without being cleaned from enamel, successively pouring with 3% hydrogen peroxide solution in ratio of dental material and solution of 1:10 per day at a temperature of +2...+8 °C and an alcohol-ether mixture, containing 1 part of alcohol and 3 parts of ether, in ratio of material and mixture of 1:5 for a day at room temperature, after which each tooth is washed with distilled water and dried on filter paper, demineralization is carried out in solution of 1.8 or 2.4 N hydrochloric acid with a volume-weight ratio of the biomaterial to acid of 1:5 or 1:10 with changing the demineralizing solution once every three days, during neutralization, bringing the pH of solution to 8; precipitate separated by centrifugation is twice washed with distilled water, dried at 120 °C for 8 hours, ground to powdery state in a pharmacy mortar and sterilized. USE - Medicine; pharmaceutics. ADVANTAGE - Method provides higher yield of the mineral bone component as compared to the prototype. 1 cl, 4 tbl |
| IPC 分类号 | A61K-035/32 ; A61L-027/00 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/20516 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | UNIV SAMARA NAT RES (UYSA-Non-standard) |
| 推荐引用方式 GB/T 7714 | VLASOV M YU,PISAREVA E V,KOVNIR O I,et al. METHOD OF PRODUCING ALLOGENIC AND XENOGENIC MINERAL BONE COMPONENT FROM HUMAN AND ANIMAL DENTAL TISSUES. RU2829913-C1[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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