| New tetrabenazine intermediate Q salt for synthesizing tetrabenazine, valbenazine and deutetrabenazine | |
| 2023-09-13 | |
| 专利权人 | RK PHARMA INC (RKPH-Non-standard) |
| 申请日期 | 2023-09-13 |
| 专利号 | IN202341061463-A |
| 成果简介 | NOVELTY - Tetrabenazine intermediate Q salt (I) is new. USE - Tetrabenazine intermediate Q salt for synthesizing tetrabenazine (claimed), valbenazine and deutetrabenazine. ADVANTAGE - The tetrabenazine intermediate Q salt preparation method is cost effective, has simple and safer process conditions, ensures higher yield and quality, and uses commercially low cost raw materials. DETAILED DESCRIPTION - Tetrabenazine intermediate Q salt of formula (I) is new. INDEPENDENT CLAIMS are included for: (1) a method for preparing the tetrabenazine intermediate Q salt; and (2)a method for preparing the tetrabenazine compound, which involves reacting 3-[(dimethylamino)methyl]-5-methylhexan-2-one with dimethyl sulfate in presence of suitable solvent to obtain the tetrabenazine intermediate Q salt, reacting with 6,7- dimethoxy-3,4-dihydroisoquinoline-hydrochloride of formula (IV) in presence of suitable solvent and suitable base to obtain the product. |
| IPC 分类号 | C07C-221/00 ; C07C-225/06 ; C07D-217/02 ; C07D-307/89 ; C07D-455/06 |
| 国家 | 印度 |
| 专业领域 | 医药卫生 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/20416 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | RK PHARMA INC (RKPH-Non-standard) |
| 推荐引用方式 GB/T 7714 | DOPPALAPUDI S,REDDY K S,KANAGARAJ S,et al. New tetrabenazine intermediate Q salt for synthesizing tetrabenazine, valbenazine and deutetrabenazine. IN202341061463-A[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。
修改评论