Bilosomal glibenclamide gel formulation for enhanced bioavailability in the brain, comprises glibenclamide, sodium deoxycholate, mixture of cholesterol and sorbitan monopalmitate
2023-09-14
专利权人UNIV SHOOLINI BIOTECHNOLOGY & MANAGEMENT (USLN-C)
申请日期2023-09-14
专利号IN202311061902-A
成果简介NOVELTY - Bilosomal glibenclamide gel formulation comprises 3 mg glibenclamide, 5-25 mg sodium deoxycholate, 100-300 mg mixture of cholesterol and Span(RTM: Sorbitan monopalmitate) 40 in a weight ratio of 1:1-1:9. USE - Bilosomal glibenclamide gel formulation for enhanced bioavailability in the brain. ADVANTAGE - The bilosomal glibenclamide gel formulation exhibits a drug release efficiency of 86.54% at 12 hours, and exhibits an entrapped efficiency of 35-70%, and holds immense potential in advancing neurological therapies.
IPC 分类号A61K-031/4375 ; A61K-031/475 ; A61K-031/64 ; A61K-047/10 ; A61K-047/26 ; A61K-009/00 ; A61K-009/127
国家印度
专业领域医药卫生
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/20397
专题中国科学院新疆生态与地理研究所
作者单位
UNIV SHOOLINI BIOTECHNOLOGY & MANAGEMENT (USLN-C)
推荐引用方式
GB/T 7714
TRIPATHI M,KAURAV H. Bilosomal glibenclamide gel formulation for enhanced bioavailability in the brain, comprises glibenclamide, sodium deoxycholate, mixture of cholesterol and sorbitan monopalmitate. IN202311061902-A[P]. 2023.
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