New salts of Mavacamten compound having compound of Mavacamten compound
2023-09-19
专利权人MANKIND PHARMA LTD (MANK-Non-standard)
申请日期2023-09-19
专利号IN202311062812-A
成果简介NOVELTY - Salts of Mavacamten compound (I) having compound of Mavacamten compound (II)-(IV), is new. USE - Salts of Mavacamten compound. ADVANTAGE - The mavacamten compound is pure novel salt, isolated as crystalline or amorphous solid having purity of 99.5% as measured by high-Performance Liquid Chromatography (HPLC), improve functional capacity and symptoms. DETAILED DESCRIPTION - Salts of Mavacamten compound of formula (I) having compound of Mavacamten compound of formulae (II)-(IV), is new. M=monovalent or bivalent metal and X is selected from organic/inorganic acid or base. An INDEPENDENT CLAIM is included for process for the preparation of Mavacamten freebase compound of formula I from its acceptable salts, which involves: (i) providing a solution of salts of Mavacamten compound of formula (I) in one or more solvents, (ii) adding suitable acid to the above solution, and (iii) isolating the Mavacamten compound of formula (I).
IPC 分类号A61K-031/513 ; A61K-047/32 ; A61K-047/38 ; A61P-009/00 ; C07D-239/10 ; C07D-239/545
国家印度
专业领域医药卫生
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/20348
专题中国科学院新疆生态与地理研究所
作者单位
MANKIND PHARMA LTD (MANK-Non-standard)
推荐引用方式
GB/T 7714
GOSHWAMI L,KUMAR N,PANDEY V P,et al. New salts of Mavacamten compound having compound of Mavacamten compound. IN202311062812-A[P]. 2023.
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