| METHOD FOR PREDICTION OF EXACERBATIONS IN BRONCHIAL ASTHMA OF MILD AND MODERATE SEVERITY | |
| 2023-10-05 | |
| 专利权人 | AS SIBE PHYSIOLOGY & PATHOLOGY SCI CENT (ASIP-Non-standard) |
| 申请日期 | 2023-10-05 |
| 专利号 | RU2835342-C1 |
| 成果简介 | NOVELTY - Invention refers to medicine, namely to pulmonology, and can be used for prediction of exacerbations in bronchial asthma (BA) of mild and moderate severity. Patient’s whole venous blood is collected, lymphocytes are recovered on density gradient by centrifugation. Subpopulations of CD4+ and CD8+ are recovered from the total population of lymphocytes, and percentage ratio of cells in subpopulations is determined by 5 levels of energy state, as shown in figure 1: 1 – cells with very high mitochondrial membrane potential (MMP) (MMP-1), 2 – cells with high MMP (MMP-2), 3 – cells with average MMP (MMP-3), 4 – cells with reduced MMP (MMP-4), 5 – cells with low MMP (MMP-5), further, a risk coefficient (Cr) of the onset of BA exacerbations is calculated in standard units (s.u.) by formula. At value of Cr≥100 s.u., low risk of asthma exacerbations is predicted; at value Cr<100 s.u., high risk of exacerbations is predicted. USE - Medicine. ADVANTAGE - Invention enables to reliably predict the risk of BA exacerbations, which is necessary for controlling the disease and effective treatment of patients. 1 cl, 1 dwg, 1 tbl, 4 ex |
| IPC 分类号 | A61B-005/00 ; G01N-033/48 ; G01N-033/53 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/20121 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | AS SIBE PHYSIOLOGY & PATHOLOGY SCI CENT (ASIP-Non-standard) |
| 推荐引用方式 GB/T 7714 | VITKINA T I,KONDRATYEVA E,MINEEVA E E,et al. METHOD FOR PREDICTION OF EXACERBATIONS IN BRONCHIAL ASTHMA OF MILD AND MODERATE SEVERITY. RU2835342-C1[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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