METHOD FOR PRE-IMPLANTATION TREATMENT OF BIOLOGICAL PROSTHESES FOR CARDIOVASCULAR SURGERY
2023-10-09
专利权人SUPERHARD & NEW CARBON MATERIALS INST (SUPE-Non-standard)
申请日期2023-10-09
专利号RU2827028-C1
成果简介NOVELTY - Invention relates to a method for pre-implantation treatment of biological prostheses for cardiovascular surgery. Method for pre-implantation treatment of biological prostheses for cardiovascular surgery involves immersion in an aqueous solution of glycerol, content of which is 50–60%, pre-washed from preserving solution of biological prostheses, drying of biological prostheses and their sterilization with ethylene oxide, characterized in that the incubation time in the glycerol solution is 16–24 hours, to increase bio- and hemocompatibility, an anticoagulant is added to the glycerol solution—unfractionated or low-molecular heparin in a final concentration of 10–100 ED/ml, drying of the biological prosthesis takes place in a vacuum chamber for 6 hours at an overpressure of (−0.07) MPa. USE - Medicine. ADVANTAGE - Above described method enables to perform pre-implantation treatment of prostheses for cardiovascular surgery with increase of their bio- and hemocompatibility. 1 cl, 2 dwg, 1 tbl, 1 ex
IPC 分类号A01N-001/02 ; A61K-031/727 ; A61L-027/00
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/20096
专题中国科学院新疆生态与地理研究所
作者单位
SUPERHARD & NEW CARBON MATERIALS INST (SUPE-Non-standard)
推荐引用方式
GB/T 7714
KUDRYAVTSEVA YU A,OVCHARENKO E A,REZVA M A,et al. METHOD FOR PRE-IMPLANTATION TREATMENT OF BIOLOGICAL PROSTHESES FOR CARDIOVASCULAR SURGERY. RU2827028-C1[P]. 2023.
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