METHOD OF TREATING OPTIC DISC PIT
	SHKVORCHENKO D O; KASHTAN O V; PISMENSKAYA V A; MORINA N A; PETUKHOVA A A
	2023-10-20
专利权人	RUSSIAN FEDERATION MIN HEALTH CHILDRENS (RUHE-Non-standard)
申请日期	2023-10-20
专利号	RU2826136-C1
成果简介	NOVELTY - Invention can be used for surgical treatment of optic disc pit. That is ensured by subtotal microinvasive vitrectomy. Posterior hyaloid membrane of the vitreous body is removed. Then, internal limiting membrane (ILM) is mobilized by disposable endovitreal forceps by method of circular "petal" membranorhexis at 270 degrees around foveola, with size of removed membrane 2.5 diameters of optic disc. ILM is separated from the periphery to the center by separate sections along the meridians. ILM flap is left attached to the temporal edge of the disc and covers the optic disc defect. Endolaser coagulation is performed along the optic disc edge from the temporal side. Further, intraoperative exchange of fluid for air is performed through 27 G cannula. 0.05 ml of prepared autologous platelet-rich plasma (PRP) is introduced intravitreal; the distal end of the cannula is placed above the optic disc. Excessive PRP is visually controlled, passively aspirated, and localized in optic nerve disc. USE - Medicine; ophthalmology. ADVANTAGE - Invention provides higher visual acuity and anatomical closure of optic disc pit due to the high content of growth and trophic factors and fibrin, which provides mechanical support by creating three-dimensional networks serving as the basis for cell proliferation and differentiation processes, as well as additional fixation of the retina, due to the formation of a chorioretinal commissure, which interrupts the circulation of fluid into the subretinal space, thereby preventing neuroepithelial detachment or its progression. 1 cl, 2 ex
IPC 分类号	A61F-009/007 ; A61F-009/008 ; A61K-035/19 ; A61P-027/02
国家	俄罗斯
专业领域	生物科学
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/19474
专题	中国科学院新疆生态与地理研究所
作者单位	RUSSIAN FEDERATION MIN HEALTH CHILDRENS (RUHE-Non-standard)
推荐引用方式 GB/T 7714	SHKVORCHENKO D O,KASHTAN O V,PISMENSKAYA V A,et al. METHOD OF TREATING OPTIC DISC PIT. RU2826136-C1[P]. 2023.

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