USE OF ALCOHOLIC EXTRACT OF AERIAL PARTS OF MARAL ROOT RHAPONTICUM CARTHAMOIDES AS AGENT, INHIBITING ACTIVITY OF CORONAVIRUS SARS-CoV-2 AND HERPES SIMPLEX VIRUS TYPE 2 IN VITRO AND METHOD FOR PRODUCTION THEREOF
2023-10-30
专利权人SUPERHARD & NEW CARBON MATERIALS INST (SUPE-Non-standard)
申请日期2023-10-30
专利号RU2825393-C1
成果简介NOVELTY - Invention relates to a method of producing an alcoholic extract of maral root Rhaponticum carthamoides. Method of producing alcoholic extract of maral root Rhaponticum carthamoides, including collection, grinding and drying of plants, extraction in aqueous solution of ethyl alcohol, drying of alcoholic extract, wherein to obtain an alcoholic extract having antiviral activity against coronavirus SARS-CoV-2 and herpes simplex virus type 2 HSV-2 in vitro, aerial parts of the plant are used during the flowering period, extraction is carried out in 70% ethyl alcohol in a ratio of dry raw material/extracting agent by weight of 1/10 for 7 days at room temperature with rocking at rate of 100 rpm for 7 days, obtained extract is dried under aseptic conditions at 30±2 °C, then dissolved in dimethyl sulphoxide at rate of 200 mg/ml while rocking at rate of 100 rpm at room temperature for a day. USE - Medicine. ADVANTAGE - Use of the claimed invention provides an alcoholic extract of said plant for effective suppression of replication of coronavirus SARS-CoV-2 and herpes simplex virus type 2 in vitro, wherein the output of the main biologically active compound 20-hydroxyecdysone from the weight of the dry alcohol extract is 1.32 and 1.30% of the leaves and stems, respectively. 1 cl, 4 dwg, 5 tbl, 6 ex
IPC 分类号A61K-036/28 ; A61P-031/14 ; A61P-031/22
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/19416
专题中国科学院新疆生态与地理研究所
作者单位
SUPERHARD & NEW CARBON MATERIALS INST (SUPE-Non-standard)
推荐引用方式
GB/T 7714
KAZACHINSKAYA E I,IVANOVA A V,ZIBAREVA L N,et al. USE OF ALCOHOLIC EXTRACT OF AERIAL PARTS OF MARAL ROOT RHAPONTICUM CARTHAMOIDES AS AGENT, INHIBITING ACTIVITY OF CORONAVIRUS SARS-CoV-2 AND HERPES SIMPLEX VIRUS TYPE 2 IN VITRO AND METHOD FOR PRODUCTION THEREOF. RU2825393-C1[P]. 2023.
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