METHOD OF PRODUCING PREPARATION BASED ON SODIUM ALGINATE AND N-VINYLPYRROLIDONE ENRICHED WITH ACTIVE IODINE
	SOROKIN A V; LAVLINSKAYA M S; KHOLYVKA M G; ARTYUKHOV V G
	2023-11-08
专利权人	FEDERAL STATE BUDGETARY EDUCATIONAL (BUDG-Non-standard)
申请日期	2023-11-08
专利号	RU2832906-C1
成果简介	NOVELTY - Invention relates to a method of producing a preparation based on sodium alginate and N-vinylpyrrolidone enriched with active iodine. Method of producing a preparation based on sodium alginate and N-vinylpyrrolidone enriched with active iodine, involving dissolving iodine in a solution of potassium iodide in sterile water for injections, followed by adding a polysaccharide, characterized in that 5–6 g of iodine is dissolved in 30 g of 10 wt.% potassium iodide solution prepared on sterile water for injections, followed by adding 2–3 g with constant stirring at rate of 250 rpm to obtain a viscous solution, and to obtain gel—4–5 g of a graft copolymer of sodium alginate with a ratio of residues of β-D-mannuronic (M-units) and α-L-guluronic (G-units) acids M-units/G-units=1.56 and viscosity of 1 wt.% aqueous solution at 25 °C, equal to 4–12 cps, and N-vinylpyrrolidone, with content in the copolymer of graft chains of N-vinylpyrrolidone with a molecular weight of 9–10 kDa, equal to 9–10 wt.%; after which the obtained preparation is made with sterile water for injections to 50 g; filtered through a sterile nylon membrane with pore diameter of 45 mcm. USE - Chemical-pharmaceutical industry. ADVANTAGE - Said invention enables to create a preparation based on a graft copolymer of sodium alginate and N-vinylpyrrolidone, containing active iodine in amount of 10–12 wt.% and having wound healing properties. 1 cl, 4 ex
IPC 分类号	A61K-031/734 ; A61K-031/79 ; A61K-033/18
国家	俄罗斯
专业领域	生物科学
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/19324
专题	中国科学院新疆生态与地理研究所
作者单位	FEDERAL STATE BUDGETARY EDUCATIONAL (BUDG-Non-standard)
推荐引用方式 GB/T 7714	SOROKIN A V,LAVLINSKAYA M S,KHOLYVKA M G,et al. METHOD OF PRODUCING PREPARATION BASED ON SODIUM ALGINATE AND N-VINYLPYRROLIDONE ENRICHED WITH ACTIVE IODINE. RU2832906-C1[P]. 2023.

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