METHOD OF PRODUCING GLIAL DERIVATIVES OF INDUCED PLURIPOTENT STEM CELLS WITH INCREASED EXPRESSION OF NGF FOR THERAPY OF NEURODEGENERATIVE DISEASES
2023-11-09
专利权人UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
申请日期2023-11-09
专利号RU2829363-C1
成果简介NOVELTY - Invention relates to biotechnology, particularly to a method of producing glial precursors derived from induced pluripotent stem cells with increased expression of NGF for therapy of neurodegenerative diseases. USE - Biotechnology. ADVANTAGE - Invention provides obtaining a cell culture of modified glial precursors, which demonstrates expression of glial marker s100β, stimulates increased survival rate of cerebellar neurons and has pronounced antiamnestic action due to increased secretion of neurotrophin NGF. 1 cl, 2 dwg, 3 tbl, 3 ex
IPC 分类号A61K-035/12 ; C12N-005/095
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/19313
专题中国科学院新疆生态与地理研究所
作者单位
UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
推荐引用方式
GB/T 7714
GOLDSHTEYN D V,SALIKHOVA D I,MAKHNACH O V,et al. METHOD OF PRODUCING GLIAL DERIVATIVES OF INDUCED PLURIPOTENT STEM CELLS WITH INCREASED EXPRESSION OF NGF FOR THERAPY OF NEURODEGENERATIVE DISEASES. RU2829363-C1[P]. 2023.
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