| METHOD OF PRODUCING GLIAL DERIVATIVES OF INDUCED PLURIPOTENT STEM CELLS WITH INCREASED EXPRESSION OF BDNF FOR THERAPY OF ISCHEMIC STROKE | |
| 2023-11-09 | |
| 专利权人 | UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C) |
| 申请日期 | 2023-11-09 |
| 专利号 | RU2829361-C1 |
| 成果简介 | NOVELTY - Invention relates to biotechnology, in particular to a method of producing glial precursors derived from induced pluripotent stem cells with high expression of BDNF for therapy of ischemic stroke. USE - Biotechnology. ADVANTAGE - Invention provides obtaining a cell culture of modified glial precursors, which demonstrates expression of glial marker s100β, stimulates increased survival rate of cortical neurons and has anti-ischemic action consisting in reduction of death of animals and improvement of neurological deficit. 1 cl, 2 dwg, 3 tbl, 3 ex |
| IPC 分类号 | A61K-035/12 ; C12N-005/095 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/19312 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C) |
| 推荐引用方式 GB/T 7714 | GOLDSHTEYN D V,SALIKHOVA D I,MAKHNACH O V,et al. METHOD OF PRODUCING GLIAL DERIVATIVES OF INDUCED PLURIPOTENT STEM CELLS WITH INCREASED EXPRESSION OF BDNF FOR THERAPY OF ISCHEMIC STROKE. RU2829361-C1[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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