METHOD OF PRODUCING AGENT HAVING ANTIOXIDANT AND IMMUNOMODULATORY ACTIVITY BASED ON HERB TRIFOLIUM PRATENSE LINNAEUS
2023-11-28
专利权人UNIV ORENBURG MEDICAL (UYOR-Non-standard)
申请日期2023-11-28
专利号RU2828665-C1
成果简介NOVELTY - Invention relates to a method of producing Trifolium pratense L. herb extract, having antioxidant and immunomodulatory activity. Method for producing an agent having antioxidant and immunomodulatory activity from Trifolium pratense L. herb, comprising producing an extract, including loading of the calculated amount of raw material with particle size of 0.5–1.0 mm into the extractor, which is then filled with an extractant—ethyl alcohol 75 vol.% in the ratio of raw materials: extractant 1:20, extracted for 50 minutes at temperature of 50 °C in an ultrasonic bath, the obtained extraction is evaporated in vacuum to 1/5 of the initial volume, after which the extract is dehydrated, cleaned, thickened and sent for drying to a residual moisture content in the product of not more than 5 vol.%, note here that said extractor is cleaned with water purified to remove ballast substances and 50 vol.% for extraction of active substances, and drying of extract is carried out at temperature above 60 and up to 65 °C. USE - Pharmaceutical industry. ADVANTAGE - Extract obtained using the method described above is characterized by flavonoid content of 2.67 wt.%, has antioxidant and immunomodulatory properties. 1 cl, 1 tbl
IPC 分类号A61K-036/48 ; A61P-017/18 ; A61P-037/02 ; B01D-011/02
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/19157
专题中国科学院新疆生态与地理研究所
作者单位
UNIV ORENBURG MEDICAL (UYOR-Non-standard)
推荐引用方式
GB/T 7714
MIKHAILOVA I V,IVANOVA E V,SINEGOVETS A A,et al. METHOD OF PRODUCING AGENT HAVING ANTIOXIDANT AND IMMUNOMODULATORY ACTIVITY BASED ON HERB TRIFOLIUM PRATENSE LINNAEUS. RU2828665-C1[P]. 2023.
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