| Nanofiber implant composition for treating dry eye syndrome symptoms including discomfort, visual disturbances, and tears film instability, comprises drug as lifitegrast loaded nanoparticles in biodegradable polymer including polyvinyl alcohol | |
| 2023-12-02 | |
| 专利权人 | PARUL PHARM PVT LTD (PARU-Non-standard) ; DHARAMSI A (DHAR-Individual) ; PATEL L D (PATE-Individual) ; TALATI M (TALA-Individual) ; PANJWANI D (PANJ-Individual) ; PATEL A (PATE-Individual) ; SAHA N (SAHA-Individual) ; UNIV PARUL (UYPA-Non-standard) |
| 申请日期 | 2023-12-02 |
| 专利号 | IN202321082069-A |
| 成果简介 | NOVELTY - Nanofiber implant composition comprises drug loaded nanoparticles in biodegradable polymer, where the drug is lifitegrast, and the biodegradable polymer is polyvinyl alcohol, hydrophilic polymer is PluronicF-127 (RTM: copolymer of polyethylene oxide and polypropylene oxide), hydrophobic polymer is polycaprolactone, and mannitol as a cryoprotectant. USE - Nanofiber implant composition for treating dry eye syndrome symptoms including discomfort, visual disturbances, and tears film instability. No biological data given. ADVANTAGE - The nanofiber implant composition has extended-release and biodegradable effects, thus prolonging its residence time in the eye and lead to reduced instillation frequency, is safe and non-irritant to the eye. DETAILED DESCRIPTION - An INDEPENDENT CLAIM is included for a method for preparing the nanofiber implant composition, which involves: preparing lifitegrast-loaded nanoparticles in biodegradable polymers; and preparing biodegradable nanofiber implant formulation of lifitegrast from the lifitegrast-loaded nanoparticles in biodegradable polymers. |
| IPC 分类号 | A61K-047/30 ; A61K-047/34 ; A61K-047/48 ; A61K-047/69 ; A61K-009/22 ; A61K-009/52 ; B82Y-030/00 ; B82Y-005/00 |
| 国家 | 印度 |
| 专业领域 | 医药卫生 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/19091 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | 1.PARUL PHARM PVT LTD (PARU-Non-standard) 2.DHARAMSI A (DHAR-Individual) 3.PATEL L D (PATE-Individual) 4.TALATI M (TALA-Individual) 5.PANJWANI D (PANJ-Individual) 6.PATEL A (PATE-Individual) 7.SAHA N (SAHA-Individual) 8.UNIV PARUL (UYPA-Non-standard) |
| 推荐引用方式 GB/T 7714 | PATEL D J,PATEL L D,AHLAWAT P,et al. Nanofiber implant composition for treating dry eye syndrome symptoms including discomfort, visual disturbances, and tears film instability, comprises drug as lifitegrast loaded nanoparticles in biodegradable polymer including polyvinyl alcohol. IN202321082069-A[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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