| INTRANASAL ANTIVIRAL AGENT | |
| 2023-12-04 | |
| 专利权人 | UNIV URAL FEDERAL (UYUR-C) |
| 申请日期 | 2023-12-04 |
| 专利号 | RU2833350-C1 |
| 成果简介 | NOVELTY - Invention relates to an intranasal antiviral agent containing recombinant interferon alpha-2b and a natural interferon inducer from the yeast Saccharomyces cerevisiae in the form of a lyophilisate for preparing a solution for intranasal use, and can be used in medicine and pharmaceutics. Intranasal antiviral agent includes interferon, interferon inducer, dimethyl sulphoxide (DMSO) absorption activator, selected from a class of bipolar aprotic solvents and having anti-inflammatory, antiseptic, analgesic action and cryoprotective properties, polyethylene oxide, an antioxidant and a stabilizer. As an interferon inducer – a sodium salt of double-helical ribonucleic acid in the form of a substance, as an interferon – recombinant human interferon alpha-2b, as an antioxidant – Trilon B (EDTA), stabilizer is isotonic sodium chloride solution, and the ratio of dimethyl sulphoxide and double-stranded ribonucleic acid (dsRNA) is 1:4.5. USE - Medicine. ADVANTAGE - Creation of such an intranasal antiviral agent, which provides intensification of interferon synthesis and antiviral action of the preparation due to the synergistic action of the interferon inducer dsRNA and interferon in a certain ratio, as well as enhanced penetration of active components through cell membranes due to introduction of a suction activator into the composition. 1 cl, 3 dwg, 2 tbl, 4 ex |
| IPC 分类号 | A61K-031/713 ; A61K-038/21 ; A61K-047/10 ; A61K-047/20 ; A61P-031/12 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/19081 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | UNIV URAL FEDERAL (UYUR-C) |
| 推荐引用方式 GB/T 7714 | IVANOVA O S,LEVAGINA G M,DANILENKO E D,et al. INTRANASAL ANTIVIRAL AGENT. RU2833350-C1[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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