| MULTIFUNCTIONAL CONJUGATES OF IPIDACRINE WITH 2-SUBSTITUTED PHENOLS, METHOD FOR PRODUCTION THEREOF AND USE FOR TREATING NEURODEGENERATIVE DISEASES | |
| 2023-12-11 | |
| 专利权人 | POSTOVSKY ORGANIC SYNTHESIS INST (POST-Soviet Institute) ; FEDERAL STATE BUDGETARY INST (FSBI-C) |
| 申请日期 | 2023-12-11 |
| 专利号 | RU2836319-C1 |
| 成果简介 | NOVELTY - Invention relates to novel multifunctional conjugates of ipidacrine with 2-substituted phenols, which have the ability to simultaneously inhibit acetylcholinesterase and butyrylcholinesterase, bind to the peripheral anionic site of acetylcholinesterase, inhibit self-aggregation of beta-amyloid and bind free radicals. Also disclosed is a method of producing conjugates of ipidacrine with 2-substituted phenols. USE - Chemistry. ADVANTAGE - Disclosed are multifunctional conjugates of ipidacrine with 2-substituted phenols, which can be used to treat neurodegenerative diseases. 4 cl, 2 dwg, 4 tbl, 9 ex |
| IPC 分类号 | A61K-031/47 ; A61P-025/28 ; C07D-221/16 |
| 国家 | 俄罗斯 |
| 专业领域 | 化学化工 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/18990 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | 1.POSTOVSKY ORGANIC SYNTHESIS INST (POST-Soviet Institute) 2.FEDERAL STATE BUDGETARY INST (FSBI-C) |
| 推荐引用方式 GB/T 7714 | GRISHCHENKO M V,MAKHAEVA G F,SHCHEGOLKOV E V,et al. MULTIFUNCTIONAL CONJUGATES OF IPIDACRINE WITH 2-SUBSTITUTED PHENOLS, METHOD FOR PRODUCTION THEREOF AND USE FOR TREATING NEURODEGENERATIVE DISEASES. RU2836319-C1[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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