IMMOBILIZED ON HYALURONIC ACID GEL BIS(L-THREONINATE) GERMANIUM (IV) DIHYDROXIDE WITH CHEMICAL FORMULA (Ge(Thr) less than sub greater than 2 less than /sub greater than (OH) less than sub greater than 2 less than /sub greater than ) AND METHOD FOR PRODUCTION THEREOF
2023-12-15
专利权人UNIV PRIVOLZHSKY RES MEDICAL (UYPR-Non-standard)
申请日期2023-12-15
专利号RU2830110-C1
成果简介NOVELTY - Group of inventions relates to chemistry and pharmaceutics, specifically to immobilized on hyaluronic acid gel bis(L-threoninate) germanium (IV) dihydroxide with chemical formula [Ge(Thr)2(OH)2], having prolonged action antimicrobial activity, and to method of its production. Proposed method is characterized by the following steps: for preparing the gel, hyaluronic acid is mixed with distilled water in a weight ratio of (0.5-10)/100, respectively, for 30-40 minutes at room temperature; settling the obtained gel base for 12 hours and re-stirring for 30-40 minutes; then, while stirring, bis(L-threoninate) germanium (IV) dihydroxide is added to the obtained gel base in a weight ratio greater than or equal to 1/100, respectively. USE - Medicine; chemistry; pharmaceutics. ADVANTAGE - Group of inventions provides a synergistic antimicrobial effect. 2 cl, 2 tbl
IPC 分类号A61K-031/28 ; A61K-047/36 ; A61K-009/10 ; A61P-031/04 ; C07F-007/30
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/18912
专题中国科学院新疆生态与地理研究所
作者单位
UNIV PRIVOLZHSKY RES MEDICAL (UYPR-Non-standard)
推荐引用方式
GB/T 7714
KADOMTSEVA A V,MOCHALOV G M,ZASLAVSKAYA M I,et al. IMMOBILIZED ON HYALURONIC ACID GEL BIS(L-THREONINATE) GERMANIUM (IV) DIHYDROXIDE WITH CHEMICAL FORMULA (Ge(Thr) less than sub greater than 2 less than /sub greater than (OH) less than sub greater than 2 less than /sub greater than ) AND METHOD FOR PRODUCTION THEREOF. RU2830110-C1[P]. 2023.
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