| METHOD OF PRODUCING 2-(5-OXO-2,4-DIPHENYL-5,6-DIHYDRO-4H-1,3,4-THIADIAZIN-6-YL)ACETIC ACID | |
| 2023-12-20 | |
| 专利权人 | FEDERAL STATE BUDGETARY EDUCATIONAL (BUDG-Non-standard) |
| 申请日期 | 2023-12-20 |
| 专利号 | RU2831020-C1 |
| 成果简介 | NOVELTY - Invention relates to a method of producing a compound of general formula I, where R=Ph. Disclosed method is carried out by reacting N'-phenylbenzothiohydrazide with maleic anhydride in catalysis with 1,4-diazabicyclo[2.2.2]octane in molar ratio 2.1:4.1:0.8, respectively, in ethyl acetate for 24 hours at ambient temperature, the end product is separated from ethyl acetate, for which ethyl acetate is distilled off, 2 parts of chloroform and 5 parts of hexane are successively added to the residue, the obtained precipitate of the end product is filtered and dried. USE - Chemistry. ADVANTAGE - Obtaining a compound with high output, which can be used in medicine, for example, as an antihyperglycemic agent. 1 cl, 1 tbl, 2 ex |
| IPC 分类号 | A61K-031/549 ; C07B-041/00 ; C07D-285/16 |
| 国家 | 俄罗斯 |
| 专业领域 | 化学化工 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/18823 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | FEDERAL STATE BUDGETARY EDUCATIONAL (BUDG-Non-standard) |
| 推荐引用方式 GB/T 7714 | TRUKHANOVA I A,YUSKOVETS V N,KOVANSKOV V E,et al. METHOD OF PRODUCING 2-(5-OXO-2,4-DIPHENYL-5,6-DIHYDRO-4H-1,3,4-THIADIAZIN-6-YL)ACETIC ACID. RU2831020-C1[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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