| METHOD OF PRODUCING GENETICALLY MODIFIED RABBITS WITH LEPR GENE KNOCKOUT USING CRISPR/Cas9 SYSTEM | |
| 2023-12-21 | |
| 专利权人 | AS RUSSIA GENE BIOLOGY INST (ASGE-Non-standard) ; SUPERHARD & NEW CARBON MATERIALS INST (SUPE-Non-standard) |
| 申请日期 | 2023-12-21 |
| 专利号 | RU2836438-C1 |
| 成果简介 | NOVELTY - Invention relates to biotechnology, in particular to a genetically modified LEPR gene knockout rabbit. Said rabbit is designed to create a model of morbid obesity and lipid and carbohydrate metabolism disorders and carries a deletion in the rabbit LEPR gene, including part of exon 10, intron 10 and part of exon 11. Present invention also relates to a method of producing said genetically modified rabbit using a CRISPR/Cas9 system. USE - Biotechnology. ADVANTAGE - Present invention provides genetic modification (deletion) in the rabbit genome in the LEPRgene locus. 2 cl, 6 dwg, 7 ex |
| IPC 分类号 | A01K-067/027 ; C12N-015/00 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/18802 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | 1.AS RUSSIA GENE BIOLOGY INST (ASGE-Non-standard) 2.SUPERHARD & NEW CARBON MATERIALS INST (SUPE-Non-standard) |
| 推荐引用方式 GB/T 7714 | SHEPELEV M V,GEORGIEV P G,KOSOVSKY G YU,et al. METHOD OF PRODUCING GENETICALLY MODIFIED RABBITS WITH LEPR GENE KNOCKOUT USING CRISPR/Cas9 SYSTEM. RU2836438-C1[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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