METHOD FOR PREDICTION OF RISK OF DEVELOPING PROSTATE CANCER
2023-12-22
专利权人FEDERAL STATE BUDGETARY EDUCATIONAL (BUDG-Non-standard)
申请日期2023-12-22
专利号RU2827104-C1
成果简介NOVELTY - Invention relates to molecular genetic diagnostics in oncology, and can be used for prediction of risk of prostate cancer. What is presented is a method for predicting the risk of developing prostate cancer. Deoxyribonucleic acid DNA is recovered from peripheral venous blood. Then SNP single-nucleotide polymorphisms are analyzed: rs4430796 of the HNF1B gene C>T, rs1859962 of the CASC17 gene A>C, rs1447295 of the CASC8 gene G>T, rs6983267 CCAT2 G>T. A genomic combination is determined by a combination of alleles of the listed genes. When detecting genomic combinations of alleles of these genes: TT CC GG G/T; TT CC G/T TT; TT AA GG G/T; TT AA G/T G/T; TT AA G/T GG; TT AA G/T TT; TT A/C GG G/T; CC CC G/T G/T; CC AA GG GG; CC CC GG GG; CC CC GG TT; CC AA GG G/T—high risk of developing prostate cancer is predicted. USE - Medicine. ADVANTAGE - Development of informative diagnostic method enables to identify patients with increased risk of prostate cancer on the basis of analysis of four single-nucleotide polymorphisms simultaneously. 1 cl, 5 dwg, 1 ex
IPC 分类号C12Q-001/68
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/18776
专题中国科学院新疆生态与地理研究所
作者单位
FEDERAL STATE BUDGETARY EDUCATIONAL (BUDG-Non-standard)
推荐引用方式
GB/T 7714
MYLNIKOV A M,DEMIN A G,POLUKONOVA N V,et al. METHOD FOR PREDICTION OF RISK OF DEVELOPING PROSTATE CANCER. RU2827104-C1[P]. 2023.
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