| METHOD FOR ENHANCING ANTIMETASTATIC ACTION OF CISPLATIN AND REDUCING ITS SIDE EFFECT ON HAEMOSTASIS SYSTEM | |
| 2023-12-25 | |
| 专利权人 | AS RUSSIA TOMSK NAT RES MEDICAL CENT (ASTO-Non-standard) |
| 申请日期 | 2023-12-25 |
| 专利号 | RU2825825-C1 |
| 成果简介 | NOVELTY - Invention refers to medicine, more specifically to oncology and haemostaseology, and can be used to enhance the antimetastatic action of cisplatin and reduce its side effect on the haemostasis system. C57BL/6 female mice with transplanted Lewis lung carcinoma with a single intraperitoneal administration of cisplatin in dose of 9 mg/kg on 10th day after tumour transplantation, daily from 16th to 19th day extract is administered intragastrically, obtained from cell culture Conium maculatum L., in dose of 30 mg/kg. Main indicators of metastasis and characteristics of haemostasis are assessed on 20th day after tumour grafting. USE - Medicine. ADVANTAGE - Invention provides reducing the number and area of lung metastases, as well as significant changes in the parameters of the haemostasis system. 1 cl, 4 dwg, 1 tbl, 1 ex |
| IPC 分类号 | A61K-033/243 ; A61K-036/26 ; A61P-035/04 ; G09B-023/28 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/18740 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | AS RUSSIA TOMSK NAT RES MEDICAL CENT (ASTO-Non-standard) |
| 推荐引用方式 GB/T 7714 | FILONOVA M V,FEDOROVA E P,RYBALKINA O YU,et al. METHOD FOR ENHANCING ANTIMETASTATIC ACTION OF CISPLATIN AND REDUCING ITS SIDE EFFECT ON HAEMOSTASIS SYSTEM. RU2825825-C1[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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