| METHOD OF PRODUCING RABBIT WITH GENE CSN2 KNOCKOUT | |
| 2023-12-28 | |
| 专利权人 | UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C) |
| 申请日期 | 2023-12-28 |
| 专利号 | RU2834016-C1 |
| 成果简介 | NOVELTY - Invention relates to biotechnology, in particular to a method for producing a rabbit with gene knockout CSN2 (β-cas). Said method involves editing the CSN2 (β-cas) by CRISPR/Cas9 method, for which zygotes, assessed as normal, are subjected to microinjection procedure with genetic construct, which is a mixture of sgRNA and CRISPR/Cas9 enzyme in ratio 1:1, living embryos are separated from dead ones as a result of microinjection and embryos are transplanted to female recipients. USE - Biotechnology. ADVANTAGE - Present invention enables to obtain a rabbit with a CSN2 (β-cas) gene knockout, capable of secreting rabbit milk without β-casein. 1 cl, 3 dwg, 5 ex |
| IPC 分类号 | A01K-067/0276 ; C12N-015/00 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/18627 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C) |
| 推荐引用方式 GB/T 7714 | POKROVSKII M V,LUGOVSKAIA E S,POKROVSKY V M,et al. METHOD OF PRODUCING RABBIT WITH GENE CSN2 KNOCKOUT. RU2834016-C1[P]. 2023. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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