METHOD FOR LABORATORY DIAGNOSIS OF CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION IN PATIENTS WITH DIABETES MELLITUS BASED ON ANALYSIS OF PROTEIN PROFILE OF BLOOD SERUM EXOSOME FRACTION
2024-01-09
专利权人KIROV MILITARY-MED ACAD (KIRO-Non-standard)
申请日期2024-01-09
专利号RU2832391-C1
成果简介NOVELTY - Invention refers to medicine, namely to cardiology, and can be used for laboratory diagnosis of chronic heart failure (CHF) with preserved ejection fraction in patients with diabetes mellitus on the basis of analysis of protein profile of blood serum exosome fraction. Mass-spectrometric identification of proteins of serotransferrin, albumin, alpha-1-antitrypsin and fibrinogen, and assessment of their concentrations in blood serum. At reference values: serotransferrin 315.9-3,673.6 mcg/l; albumin 1,828.1-6,567.0 mcg/l; alpha-1-antitrypsin and beta-chains of fibrinogen 248.8-1,611.1 mcg/l, a diagnosis of CHF is established. USE - Medicine. ADVANTAGE - Method enables reliable diagnosis of chronic heart failure with preserved ejection fraction in patients with diabetes mellitus by analysing the protein profile of the blood serum exosome fraction by electrophoresis of proteins in polyacrylamide gel and subsequent identification of proteins. 1 cl, 2 dwg, 2 tbl, 2 ex
IPC 分类号G01N-030/72 ; G01N-033/49 ; G01N-033/68
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/18515
专题中国科学院新疆生态与地理研究所
作者单位
KIROV MILITARY-MED ACAD (KIRO-Non-standard)
推荐引用方式
GB/T 7714
SVEKLINA T S,KOLIUBAEVA S N,OKTYSIUK P D,et al. METHOD FOR LABORATORY DIAGNOSIS OF CHRONIC HEART FAILURE WITH PRESERVED EJECTION FRACTION IN PATIENTS WITH DIABETES MELLITUS BASED ON ANALYSIS OF PROTEIN PROFILE OF BLOOD SERUM EXOSOME FRACTION. RU2832391-C1[P]. 2024.
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