| METHOD FOR NON-INVASIVE MONITORING OF POLYMER SCAFFOLD BIODEGRADATION | |
| 2024-01-17 | |
| 专利权人 | AS RUSSIA FUNDAMENTALS BIOTECHNOLOGY FED (ASFU-Non-standard) |
| 申请日期 | 2024-01-17 |
| 专利号 | RU2832295-C1 |
| 成果简介 | NOVELTY - Invention relates to biotechnology, namely to a method for non-invasive monitoring of biodegradation of a polymer scaffold with a fluorescent label in the body of a laboratory animal in vivo. Method is implemented by preparing a scaffold with a fluorescent label and implanting it into the body of an animal. Indocyanine green is used as a fluorescent label in the polymer, which is introduced into the oligomers making up said polymer, to obtain 0.05-0.15 wt.% content of indocyanine green in the polymer, excitation and recording of its fluorescence is carried out in the near infrared range, and in the process of monitoring, magnetic resonance imaging in the T2 FSE mode is additionally performed, and then the MRI images of the animal are analysed. USE - Biotechnology. ADVANTAGE - Method provides higher accuracy and information value of determining kinetics of biodegradation of polymer scaffold. 2 cl, 7 dwg |
| IPC 分类号 | A61B-005/055 ; A61L-027/58 ; G01N-021/00 ; G01N-024/00 ; G01N-033/533 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/18415 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | AS RUSSIA FUNDAMENTALS BIOTECHNOLOGY FED (ASFU-Non-standard) |
| 推荐引用方式 GB/T 7714 | LIKHOV A R,DEMIN D YU,VOLODINA V N,et al. METHOD FOR NON-INVASIVE MONITORING OF POLYMER SCAFFOLD BIODEGRADATION. RU2832295-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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