METHOD OF PRODUCING PURE LIGNAN PREPARATIONS FROM COMPRESSION WOOD
2024-02-15
专利权人UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
申请日期2024-02-15
专利号RU2827101-C1
成果简介NOVELTY - Invention relates to pharmaceutical industry, namely to a method of producing pure lignan preparations from compression wood. Method of producing pure preparations of lignans from compression wood, which consists in preparing the raw material used, extracting extractive substances with subsequent production of individual components, characterized by that the raw material used is compression wood of pine, spruce, fir or larch, preparation of which is carried out by drying, grinding to particle size of not more than 1 mm and subsequent drying in a vacuum drying cabinet at temperature of 40 °C, after which the obtained dry sawdust is extracted in a Soxhlet apparatus in two steps: hexane and acetone for 8 hours each, further, the acetone extract is evaporated on a rotary evaporator to a minimum volume, a five-fold excess of deionised water is added to obtain a suspension and freeze-dried, and to isolate pure preparations of lignans, a method of supercritical fluid chromatography on a stationary phase modified with polyethylene glycol is used. USE - Pharmaceutics. ADVANTAGE - Said invention enables to obtain pure lignan preparations with high biological activity. 1 cl, 3 dwg, 1 tbl, 4 ex
IPC 分类号A61K-031/05 ; A61K-036/15 ; B01D-011/02
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/18112
专题中国科学院新疆生态与地理研究所
作者单位
UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
推荐引用方式
GB/T 7714
ONUCHINA A A,FALEVA A V,DANILOVA E V,et al. METHOD OF PRODUCING PURE LIGNAN PREPARATIONS FROM COMPRESSION WOOD. RU2827101-C1[P]. 2024.
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