METHOD FOR SKIN INTEGRITY RESTORATION IN CASE OF EXTENSIVE DEEP BURNS
2024-02-27
专利权人FEDERAL STATE BUDGETARY INST (FSBI-C)
申请日期2024-02-27
专利号RU2825747-C1
成果简介NOVELTY - Invention refers to medicine, namely to surgery, combustiology, and can be used for biotechnological restoration of skin in extensive deep skin burns of III degree. Burn wound is treated by ultrasound. Then, autodermoplasty is performed with a split perforated skin graft of thickness 0.2–0.3 mm with perforation of cells in ratio of 1:6 and more. Transplantation of autologous cells of stromal-vascular fraction of adipose tissue (SVF AT) is performed, with content of autologous cells of stromal-vascular fraction of adipose tissue in amount of not less than 10×106 and viability of not less than 80%. One part of the solution is introduced into perforated cells of the transplant at depth of 0.5–1.0 mm with a frequency of at least 1 injection per 2–3 cm2, in a dose of at least 0.05 ml per injection. Second part of the solution is sprayed over the graft. USE - Medicine. ADVANTAGE - Method provides more effective engraftment of the perforated autografts, which in turn enables to reduce the length of epithelisation of the transplanted perforated autografts when introducing autologous cells of SVF AT into the burn wound during autodermoplasty, as well as avoiding postoperative complications. 5 cl, 2 ex
IPC 分类号A61B-017/00 ; A61B-017/03 ; A61K-035/35 ; A61N-007/00 ; A61P-017/02
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/17988
专题中国科学院新疆生态与地理研究所
作者单位
FEDERAL STATE BUDGETARY INST (FSBI-C)
推荐引用方式
GB/T 7714
ALEKSEEV A A,FILIMONOV K A,ZINOVYEV E V,et al. METHOD FOR SKIN INTEGRITY RESTORATION IN CASE OF EXTENSIVE DEEP BURNS. RU2825747-C1[P]. 2024.
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