METHOD FOR CORRECTION OF BEVACIZUMAB-INDUCED ARTERIAL HYPERTENSION BY UNFIXED COMBINATION OF TELMISARTAN AND AMLODIPINE
2024-02-27
专利权人UNIV KURSK STATE MEDICAL (UYKU-Non-standard)
申请日期2024-02-27
专利号RU2830480-C1
成果简介NOVELTY - Invention refers to experimental medicine, namely to cardiology. Arterial hypertension is simulated in male Wistar rats by intraperitoneal introduction of bevacizumab in dose of 15 mg/kg a week. When a cumulative dose is reached—60 mg/kg intragastrically daily 1 time day for 20 days, an unfixed combination of preparations is administered, consisting of telmisartan in dose of 3.1 mg/kg and amlodipine in dose of 0.4 mg/kg. USE - Medicine. ADVANTAGE - Method enables to correct bevacizumab-induced arterial hypertension using a non-fixed combination of preparations, which, in turn, makes it possible to expand the list of agents used to correct bevacizumab-induced arterial hypertension. 1 cl, 1 tbl, 1 ex
IPC 分类号A61K-031/4184 ; A61K-031/4422 ; A61K-039/395 ; A61P-043/00 ; A61P-009/12 ; G09B-023/28
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/17975
专题中国科学院新疆生态与地理研究所
作者单位
UNIV KURSK STATE MEDICAL (UYKU-Non-standard)
推荐引用方式
GB/T 7714
KHLYAMOV S V,ARTYUSHKOVA E B,MAL G S,et al. METHOD FOR CORRECTION OF BEVACIZUMAB-INDUCED ARTERIAL HYPERTENSION BY UNFIXED COMBINATION OF TELMISARTAN AND AMLODIPINE. RU2830480-C1[P]. 2024.
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