| METHOD OF PRODUCING AUTOPROBIOTIC BASED ON BASIC STRAINS OF HOST INTESTINAL INDIGENOUS MICROFLORA | |
| 2024-02-28 | |
| 专利权人 | BIOSNABSBYT TRADING HOUSE STOCK CO (BIOS-Non-standard) |
| 申请日期 | 2024-02-28 |
| 专利号 | RU2835594-C1 |
| 成果简介 | NOVELTY - Disclosed is a method for producing an autoprobiotic based on basic strains of indigenous intestinal microflora of a host, comprising sampling native material from patient's faeces, inoculation on a selective nutrient medium for isolating microorganisms, identification, selection of typical colonies, obtaining a pure culture, from which a lactic acid starter is prepared, wherein base microflora is Lactobacillus pentosus, Lactobacillus johnsonii, Lactobacillus fermentum, which are subjected to preliminary cultivation in at least three generations for 4-5 days each in microaerophilic conditions on a nutrient medium containing additives – bioexpressors in amount of 50-500 ppm to the weight of the nutrient medium, wherein cultivation of the first generation is carried out at temperature of 36-37 °C, second generation – at temperature of 32-34 °C, third generation – at temperature of 28-32 °C, additive for control of antagonist activity of autoprobiotic used bioexpressors resveratrol, dihydroquercetin, coenzyme Q10 and selenovite, used separately, and selective nutrient medium used is medium for lactobacilli MRS-agar. USE - Biotechnology. ADVANTAGE - Wider range of autoprobiotics based on natural microbiocenosis of host colon bacteria. 1 cl, 2 dwg, 2 tbl |
| IPC 分类号 | A23C-009/12 ; A61K-035/74 ; C12N-001/20 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/17953 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | BIOSNABSBYT TRADING HOUSE STOCK CO (BIOS-Non-standard) |
| 推荐引用方式 GB/T 7714 | SIDORENKO A I,MOLODKINA P G,SHTERMAN S V,et al. METHOD OF PRODUCING AUTOPROBIOTIC BASED ON BASIC STRAINS OF HOST INTESTINAL INDIGENOUS MICROFLORA. RU2835594-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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