METHOD FOR DIFFERENTIATED CHOICE OF PHARMACOTHERAPY OF ARTERIAL HYPERTENSION WITH UNDERLYING DORSOPATHY IN OPERATORS
2024-02-29
专利权人FEDERAL STATE BUDGETARY EDUCATIONAL (BUDG-Non-standard)
申请日期2024-02-29
专利号RU2826094-C1
成果简介NOVELTY - Invention refers to medicine, namely to pharmacogenetics, and can be used for differentiated choice of pharmacotherapy of arterial hypertension with underlying dorsopathy in operators. Pharmacogenetic testing of cytochrome P 450 CYP2C9 gene is performed. If genotypes CYP2C9*1/*2 or *2/*2 are detected for the treatment of arterial hypertension, Lozartan is used in dosage of 50 mg a day, pain syndrome is relieved by administering Meloxicam 15 mg a day in tablet form for 20 days. If observing the CYP2C9*1/*1 genotype, Amlodipine in dosage of 5 mg a day in a tablet form and Diclofenac in dosage of 75-100 mg/day in a tablet form are prescribed for 20 days. USE - Medicine. ADVANTAGE - Method provides improved occupationally significant functions in operators with arterial hypertension with underlying dorsopathy due to differentiated choice of pharmacotherapy based on pharmacogenetic testing of cytochrome P 450 CYP2C9 gene. 1 cl, 2 tbl, 2 ex
IPC 分类号A61K-031/196 ; A61K-031/4178 ; A61K-031/4422 ; A61K-031/5415 ; A61P-029/00 ; A61P-009/12 ; C12Q-001/6827 ; C12Q-001/686 ; C12Q-001/6883 ; G01N-033/58
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/17945
专题中国科学院新疆生态与地理研究所
作者单位
FEDERAL STATE BUDGETARY EDUCATIONAL (BUDG-Non-standard)
推荐引用方式
GB/T 7714
BATISHCHEVA G A,GONCHAROVA N YU,KARTASHOVA E SH,et al. METHOD FOR DIFFERENTIATED CHOICE OF PHARMACOTHERAPY OF ARTERIAL HYPERTENSION WITH UNDERLYING DORSOPATHY IN OPERATORS. RU2826094-C1[P]. 2024.
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