| METHOD FOR PREDICTION OF PRESENCE OF SPERM CELLS IN HUMAN TESTICULAR TISSUE IN BIOPSY IN PATIENTS WITH AZOOSPERMIA USING RAMAN SPECTROSCOPY OF SEMINAL PLASMA | |
| 2024-03-01 | |
| 专利权人 | FEDERAL STATE BUDGETARY INST (FSBI-C) |
| 申请日期 | 2024-03-01 |
| 专利号 | RU2829263-C1 |
| 成果简介 | NOVELTY - Invention refers to medicine, namely to reproductology, andrology and clinical embryology, and can be used to predict the presence of sperm cells in human testicular tissue in patients with azoospermia. Ejaculate is collected, Raman spectroscopy of seminal plasma is performed. Seminal plasma is used, which is centrifuged for 10 minutes at 400g and 30 minutes at 3,000g, which is immersed into a hollow waveguide, from which spectral characteristics are taken by Raman microscopy. If 2,940 cm-1 spectral line intensity is higher than 2,000 standard units, absence of sperm cells in testicular tissue of patients is predicted. At intensity of the same spectral line in range of 1,000-2,000 standard units, presence of sperm cells in testicular tissue of patients is predicted. USE - Medicine. ADVANTAGE - Method provides the possibility of non-invasive evaluation of seminal plasma and prediction of sperm cells due to use of hollow waveguides for analysis of seminal plasma, non-invasiveness of procedure and absence of complicated and expensive sample preparation when obtaining an accurate picture of cell and tissue physiology. 1 cl, 1 dwg, 2 ex |
| IPC 分类号 | C12N-005/076 ; G01N-001/40 ; G01N-021/65 ; G01N-033/487 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/17915 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | FEDERAL STATE BUDGETARY INST (FSBI-C) |
| 推荐引用方式 GB/T 7714 | MAKAROVA N P,ALEKSANDROV A I,CHERNYSHEV V S,et al. METHOD FOR PREDICTION OF PRESENCE OF SPERM CELLS IN HUMAN TESTICULAR TISSUE IN BIOPSY IN PATIENTS WITH AZOOSPERMIA USING RAMAN SPECTROSCOPY OF SEMINAL PLASMA. RU2829263-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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