| METHOD FOR ASSESSING DIRECT CONTACT TOXICITY OF MICROPLASTIC PARTICLES ON MODEL OF ISOLATED MONONUCLEAR LEUKOCYTES OF PERIPHERAL BLOOD | |
| 2024-03-05 | |
| 专利权人 | FEDERAL STATE BUDGETARY EDUCATIONAL (BUDG-Non-standard) |
| 申请日期 | 2024-03-05 |
| 专利号 | RU2832331-C1 |
| 成果简介 | NOVELTY - Invention relates to biotechnology, in particular to a method for assessing direct contact toxicity of microplastic particles on a model of isolated mononuclear leukocytes of peripheral blood, involving the use of flow cytometry with visualization. For this purpose, venous blood is taken from the test subject, from which a suspension of mononuclear cells is recovered, a suspension of mononuclear cells is incubated in RPMI 1640 medium with microplastic particles with a fluorescent label and a control suspension of mononuclear cells is simultaneously incubated in RPMI 1640 medium without microplastic particles with a fluorescent label, followed by a flow cytometry study with visualization using a common leukocyte marker CD45 and vital dye 7-AAD. USE - Biotechnology. ADVANTAGE - Invention enables to obtain a relative quantitative assessment of direct contact toxicity of microplastic particles with respect to mononuclear leukocytes of peripheral blood. 1 cl, 1 dwg, 1 ex |
| IPC 分类号 | G01N-033/49 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/17862 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | FEDERAL STATE BUDGETARY EDUCATIONAL (BUDG-Non-standard) |
| 推荐引用方式 GB/T 7714 | SHITIKOVA A M,BELSKIKH E S,ATROSHCHENKO M M,et al. METHOD FOR ASSESSING DIRECT CONTACT TOXICITY OF MICROPLASTIC PARTICLES ON MODEL OF ISOLATED MONONUCLEAR LEUKOCYTES OF PERIPHERAL BLOOD. RU2832331-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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