USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-2-THIOXO-1,3,6-TRIAZASPIRO(4.4)NON-8-ENE-4,7-DIONES AS AGENTS WITH HIGH ANTIMICROBIAL ACTIVITY AGAINST STAPHYLOCOCCUS AUREUS AND CANDIDA ALBICANS
	TRETYAKOV N A; MASLIVETS A N; BALANDINA S I
	2024-03-17
专利权人	UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
申请日期	2024-03-17
专利号	RU2831126-C1
成果简介	NOVELTY - Invention relates to use of 9-aroyl-8-hydroxy-6-(2-hydroxyalkyl)-2-thioxo-1,3,6-triazaspiro[4.4]non-8-ene-4,7-diones of general formula below as agents having antimicrobial activity against S. aureus and C. albicans. In the formula R1 = H, R2 = H, Ar =4-BrC6H4 (6a); R1 = CH3, R2 = H, Ar = Ph (6b); R1 = CH3, R2 = H, Ar = 4-ClC6H4 (6c); R1 = CH3, R2 = H, Ar = 4-BrC6H4 (6d); R1 = CH3, R2 = H, Ar = 4-CH3C6H4 (6e); R1 = H, R2 = Ph, Ar = Ph (6f); R1 = H, R2 = Ph, Ar = 4-ClC6H4 (6g); R1 = CH3, R2 = Ph, Ar = 4-BrC6H4 (6h); R1 = CH3, R2 = Ph, Ar = 4-CH3C6H4 (6i); R1 = H, R2 = Bu, Ar = Ph (6j); R1 = CH3, R2 = Bu, Ar = 4-BrC6H4 (6k). USE - Chemistry. ADVANTAGE - Invention can be used in pharmacology. 1 cl, 1 tbl, 12 ex
IPC 分类号	A61K-031/4188 ; A61P-031/04 ; C07D-487/10
国家	俄罗斯
专业领域	化学化工
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/17677
专题	中国科学院新疆生态与地理研究所
作者单位	UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C)
推荐引用方式 GB/T 7714	TRETYAKOV N A,MASLIVETS A N,BALANDINA S I. USE OF 9-AROYL-8-HYDROXY-6-(2-HYDROXYALKYL)-2-THIOXO-1,3,6-TRIAZASPIRO(4.4)NON-8-ENE-4,7-DIONES AS AGENTS WITH HIGH ANTIMICROBIAL ACTIVITY AGAINST STAPHYLOCOCCUS AUREUS AND CANDIDA ALBICANS. RU2831126-C1[P]. 2024.

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