METHOD FOR COMBINED TREATMENT OF PATIENTS WITH CRITICAL ISCHEMIA OF LOWER EXTREMITIES WITH UNDERLYING DIABETES MELLITUS
2024-03-20
专利权人UNIV REAVIZ MEDICAL (UYRE-Non-standard)
申请日期2024-03-20
专利号RU2827088-C1
成果简介NOVELTY - Invention refers to medicine, namely to cardiovascular surgery, and is intended for combined treatment of patients with critical ischemia of lower extremities with underlying diabetes mellitus. After the conservative treatment and switching the patient from taking the tablet preparations for diabetes mellitus to insulin, a femoral-foot shunting is performed with a reversed autovein or a combined conduit. In the postoperative period, the patient is administered Vazaprostan two or three ampoules, Octolipen 600 mg for 10 days, then Octolipen 600 mg for 90 days; Vessel Due F 600 LSU intravenously drop-by-drop for 10 days, Vessel Due F 250 LSU tablets up to 60 days. For the whole period of postoperative inpatient and outpatient treatment, the patient undergoes anticoagulant therapy to prevent shunt thrombosis, Eliquis 2.5 mg and Thrombo ASS 100 mg are prescribed; non-steroidal anti-inflammatory drugs are administered. Under the control of endocrinology at the stage of hospital treatment, daily glucometry is performed with correction of glucose level by subcutaneous administration of insulin; Actovegin 10.0 ml is introduced intravenously drop-by-drop for 10 days, then Actovegin 5.0 ml is introduced intramuscularly for 10 days, then Actovegin in capsules is introduced for 120 days; Neuromultivit is introduced intramuscularly for 10 days, then Neuromultivit in tablets for 30 days. On 4th postoperative day, the patency of the femoral-foot shunt is controlled and Slavinorm is administered intramuscularly for 10 injections. USE - Medicine. ADVANTAGE - Invention allows to normalize vascular wall endothelial functions, to stimulate angiogenesis on working shunt in case of shin artery occlusion. 1 cl, 2 ex
IPC 分类号A61F-002/01 ; A61K-031/192 ; A61K-031/385 ; A61K-031/407 ; A61K-031/4415 ; A61K-031/51 ; A61K-031/52 ; A61K-031/5375 ; A61K-031/616 ; A61K-031/714 ; A61K-031/726 ; A61K-035/14 ; A61K-035/44 ; A61P-003/10 ; A61P-009/10
国家俄罗斯
专业领域生物科学
语种英语
成果类型专利
文献类型科技成果
条目标识符http://119.78.100.226:8889/handle/3KE4DYBR/17615
专题中国科学院新疆生态与地理研究所
作者单位
UNIV REAVIZ MEDICAL (UYRE-Non-standard)
推荐引用方式
GB/T 7714
KRIVOSHCHEKOV Y P,KOMPANIETS V P,ROMANOV V E,et al. METHOD FOR COMBINED TREATMENT OF PATIENTS WITH CRITICAL ISCHEMIA OF LOWER EXTREMITIES WITH UNDERLYING DIABETES MELLITUS. RU2827088-C1[P]. 2024.
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