| METHOD FOR PHENOTYPE DETERMINATION OF STRESSED RATS WITH SIMULATED PHOBIC ANXIETY DISORDER | |
| 2024-03-21 | |
| 专利权人 | UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C) |
| 申请日期 | 2024-03-21 |
| 专利号 | RU2830034-C1 |
| 成果简介 | NOVELTY - Invention refers to experimental medicine, namely psychoneuropharmacology. Rats are exposed to predatory stress by exposure to fox urine in amount of 100 ml for 10 minutes daily for 10 days. Two hours after the last exposure to fox urine, behavioural activity is examined in an elevated plus maze (EPM) test for five minutes. Anxiety index (AI) and the number of freezing acts (FR) are determined. Derived values of AI and FR are used to determine behavioural phenotypes of stressed animals. USE - Medicine. ADVANTAGE - Method enables producing an experimental model of chronic stress for preclinical tests of pharmacological preparations for the purpose of correcting stress phobic anxiety disorders. 1 cl, 3 tbl, 1 ex |
| IPC 分类号 | A61B-005/16 ; G09B-023/28 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/17598 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | UNIV MISIS NAT SCI & TECHNOLOGY (UMNS-C) |
| 推荐引用方式 GB/T 7714 | TSEILIKMAN V E,TSEILIKMAN O B,SHATILOV V A,et al. METHOD FOR PHENOTYPE DETERMINATION OF STRESSED RATS WITH SIMULATED PHOBIC ANXIETY DISORDER. RU2830034-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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