| METHOD FOR PREVENTING ATROPHY, INCREASED FATIGUE OF SLOW MUSCLE FIBRES AND THEIR TRANSFORMATION INTO FAST MUSCLE FIBRES IN SOLEUS MUSCLE | |
| 2024-04-03 | |
| 专利权人 | FEDERAL STATE BUDGETARY INST (FSBI-C) |
| 申请日期 | 2024-04-03 |
| 专利号 | RU2834246-C1 |
| 成果简介 | NOVELTY - Invention refers to medicine, namely to physiology. Prevention of growth of mRNA expression of atrophy markers MuRF1 and Atrogin-1, as well as reduction of content of 18S rRNA and 28S rRNA. For this purpose, MITOKIN MOTS-C is administered intraperitoneally in dosage of 40 mg/kg in 0.9% NaCl solution with underlying 7-day functional relief. USE - Medicine. ADVANTAGE - Method enables to prevent atrophy, increased fatigue of slow muscle fibres and their transformation into fast muscle fibres in soleus muscle in experiment during functional unloading with introduction of MOTS-c. 1 cl, 9 dwg |
| IPC 分类号 | A61K-038/04 ; A61P-001/00 ; A61P-021/00 |
| 国家 | 俄罗斯 |
| 专业领域 | 生物科学 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/17393 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | FEDERAL STATE BUDGETARY INST (FSBI-C) |
| 推荐引用方式 GB/T 7714 | SIDORENKO D A,SHARLO K A,LVOVA I D,et al. METHOD FOR PREVENTING ATROPHY, INCREASED FATIGUE OF SLOW MUSCLE FIBRES AND THEIR TRANSFORMATION INTO FAST MUSCLE FIBRES IN SOLEUS MUSCLE. RU2834246-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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