| METHOD OF PRODUCING HIGHLY CONCENTRATED SOLUTION OF RIAMILOVIR | |
| 2024-04-04 | |
| 专利权人 | UNIV TYUMEN STATE MEDICAL (UYTY-Non-standard) |
| 申请日期 | 2024-04-04 |
| 专利号 | RU2830367-C1 |
| 成果简介 | NOVELTY - Invention relates to a method of producing a highly concentrated solution of riamilovir, which involves mixing riamilovir and sulphuric acid with concentration of not less than 15% in a weight ratio of 1:3. Obtained solution is extracted with ethyl acetate until decolouration, then the solution is evaporated, filtered and dried using a rotary evaporator. Obtained NH-acid form of riamilovir is mixed with meglumine in an equimolar ratio, water is added in an amount of not less than 30 wt.% of the weight of the mixture of the NH-acid form of riamilovir with meglumine and intensively stirred until complete dissolution. USE - Chemistry. ADVANTAGE - Obtaining highly concentrated solution of riamilovir in water with content of NH-acid form of riamilovir up to 41.4% by weight. 1 cl, 1 ex |
| IPC 分类号 | A61K-031/4196 ; A61K-031/53 ; A61K-047/26 ; A61K-009/08 |
| 国家 | 俄罗斯 |
| 专业领域 | 化学化工 |
| 语种 | 英语 |
| 成果类型 | 专利 |
| 文献类型 | 科技成果 |
| 条目标识符 | http://119.78.100.226:8889/handle/3KE4DYBR/17369 |
| 专题 | 中国科学院新疆生态与地理研究所 |
| 作者单位 | UNIV TYUMEN STATE MEDICAL (UYTY-Non-standard) |
| 推荐引用方式 GB/T 7714 | PRIKHODKO I S,PETROV A YU,KNYSH O I,et al. METHOD OF PRODUCING HIGHLY CONCENTRATED SOLUTION OF RIAMILOVIR. RU2830367-C1[P]. 2024. |
| 条目包含的文件 | 条目无相关文件。 | |||||
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