HUMAN ROTAVIRUS INFECTION VACCINE BASED ON ROTAVIRUS VIRUS-LIKE PARTICLES
	GREBENNIKOVA T V; ELISEEVA O V; KOSTINA L V; LATYSHEV O E; FILATOV I E; CHEREPUSHKIN S A; TSIBEZOV V; ZAIKOVA O N; SAVOCHKINA T E; PLOTNIKOV A A; LEBEDEVA V V; LOSICH M A; KHAMETOVA K M; NORKINA S N; SILAENKOVA M M; IUZHAKOVA K A; KULIKOVA N YU; ALIMBAROVA L M; LAZARENKO A A; BANKOVSKAIA N P; KRESTIANOVA T V; IVANOVA Z B; GINTSBURG A L
	2024-04-07
专利权人	FEDERAL STATE BUDGETARY INST (FSBI-C)
申请日期	2024-04-07
专利号	RU2829862-C1
成果简介	NOVELTY - Invention relates to a rotavirus vaccine based on rotavirus virus-like particles. Vaccine contains recombinant virus-like particles (VLP), formed by nucleocapsid proteins VP2, VP6 and surface proteins VP4 and VP7 of 6 genotypes G1, G2, G4, G9, P4, P8 of rotavirus type A, synthesized in a baculovirus expression system—30–120 mcg; potassium dihydrophosphate—0.30 mg; disodium hydrogen phosphate—0.31 mg; sodium chloride—2.01 mg; potassium chloride—0.04 mg; calcium chloride—0.03 mg; tris(hydroxymethyl)aminomethane—0.04 mg; thiomersal—not more than 4.5 mcg; water-oil adjuvant based on squalene—0.25 ml, water for injections—up to 0.5 ml. USE - Biotechnology; immunology; virology. ADVANTAGE - Invention provides creating a vaccine which induces specific immunity against an infection caused by human rotavirus A. 4 cl, 6 dwg, 2 tbl, 5 ex
IPC 分类号	A61K-039/15
国家	俄罗斯
专业领域	生物科学
语种	英语
成果类型	专利
文献类型	科技成果
条目标识符	http://119.78.100.226:8889/handle/3KE4DYBR/17334
专题	中国科学院新疆生态与地理研究所
作者单位	FEDERAL STATE BUDGETARY INST (FSBI-C)
推荐引用方式 GB/T 7714	GREBENNIKOVA T V,ELISEEVA O V,KOSTINA L V,et al. HUMAN ROTAVIRUS INFECTION VACCINE BASED ON ROTAVIRUS VIRUS-LIKE PARTICLES. RU2829862-C1[P]. 2024.

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